Lumbrokinase
High-Purity Earthworm-Derived Lumbrokinase for Specialized Enzyme Formulations
Lumbrokinase is a fibrinolytic enzyme complex derived exclusively from earthworms (Eisenia fetida) through a dedicated extraction and enzymatic hydrolysis process.
At Allworms Bio-Tech, we focus on authentic earthworm-derived lumbrokinase systems rather than general blended fibrinolytic enzyme products.
Supported by our own earthworm cultivation base and in-house manufacturing facility, our production system is designed to provide better raw material control, batch consistency, and traceability throughout the extraction process.
Our lumbrokinase is widely used in dietary supplement, enzyme ingredient, and functional formulation applications. Because activity values may vary depending on assay systems and testing methodologies, we work closely with global B2B customers to support product evaluation and application compatibility.
100g free sample available
MOQ: 1.5 kg
Delivery time: within 7–15 days after payment
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Pure Earthworm-Derived Lumbrokinase Manufacturer |Bulk Supply
Allworms Bio-Tech Co., Ltd is a specialized manufacturer of earthworm-derived extracts, focusing on the production of authentic lumbrokinase through controlled raw material sourcing, enzymatic extraction, and in-house manufacturing.
Unlike blended fibrinolytic enzyme systems commonly found in the market, our lumbrokinase is derived exclusively from earthworms (Eisenia fetida) using a dedicated extraction and purification process.
With our own earthworm cultivation base and production facility located in Conghua, Guangzhou, Guangdong, China, we maintain better consistency and traceability across batches.
What Is Lumbrokinase?
Lumbrokinase is a group of fibrinolytic enzymes extracted from earthworms. It has attracted attention in the dietary supplement and enzyme ingredient market because of its fibrin-related enzymatic activity.
Our lumbrokinase is produced through an enzymatic hydrolysis process followed by filtration, freeze drying, pulverization, and controlled packaging.
Main Product Features
- Pure earthworm-derived lumbrokinase
- Non-blended enzyme system
- In-house manufacturing and extraction
- Controlled raw material supply from our own breeding base
- Available in different activity grades
- Suitable for dietary supplement and enzyme formulation applications
- Batch-based production and quality control
Manufacturing & Extraction Process
Our production process is designed to maintain raw material consistency and support stable enzymatic performance.
Production Flow
Sorting → Washing → Freezing → Storage
Thawing → Washing → Grinding into slurry → Tank loading → Fermentation (enzymatic hydrolysis)
Filtration → Freeze drying → Pulverization → Sieving
Packaging → Warehousing
Why Our Process Matters
- Controlled raw material sourcing
- Dedicated earthworm extraction system
- Batch traceability
- In-house process management
- Reduced dependency on third-party raw materials

Specifications
| Feature | |
| Product Name | Lumbrokinase |
| Material Source | Fresh earthworm (Lumbricus rubellus / Eisenia fetida) |
| Appearance | Light yellow to brown powder |
| Technology Process | Enzymatic hydrolysis |
| Assay Method | Fibrin Plate Assay |
| Smell | Special fishy smell |
| Storage | Cool dry place |
| Shelf Life | 2 Years |
| Package | 1.5kg/ bag 9kg/ctn |
| Specification | |
| Activity | 10000IU/mg-200000IU/mg |
| PH value | 6–8 |
| Moisture | ≤8 |
| Ash | ≤9 |
| Selenium | ≈3 |
| Arsenic | ≤0.5 |
| Cadmium | ≤2mg/kg |
| Lead | 0.064 |
| Mercury | ND |
| Aerobic plate count | <10 |
| Staphylococcus aureus | ND |
| Moulds and yeasts | <10 |
| Coliforms | <0.3 |
| Salmonella | ND |
Understanding Lumbrokinase Activity Units
Lumbrokinase activity may be expressed using different unit systems depending on assay methodology and market practice, including:
- IU/mg
- FU/g
- LKU
- Other fibrinolytic activity systems
Different assay systems may produce significantly different numerical values.
Important Note About Activity Testing
Our internal activity evaluation is based on our fibrin plate assay method specifically developed for earthworm-derived lumbrokinase.
Because assay methods, substrates, enzyme systems, incubation conditions, and calculation methods differ across laboratories, activity values from different testing systems may not be directly comparable.
This is especially important when comparing:
- Pure earthworm-derived lumbrokinase
- General fibrinolytic enzyme systems
- Multi-enzyme or blended fibrinolytic products
- Different commercial assay standards
For this reason, we recommend that customers confirm assay methodology and testing standards before comparing activity values from different suppliers.
Pure Earthworm-Derived Lumbrokinase
At Allworms Bio-Tech, we focus specifically on earthworm-derived extracts.
Our lumbrokinase system is designed around authentic earthworm-derived enzyme production rather than general blended fibrinolytic enzyme systems.
Our Advantages
- Dedicated earthworm biotechnology manufacturer
- Own breeding base and production facility
- Controlled raw material supply chain
- Specialized extraction process
- In-house production management
- Batch consistency focus
- Long-term supply capability
Stability & Handling
Lumbrokinase is an enzyme-sensitive material. Storage and transportation conditions may influence activity performance.
Recommended Handling
- Store in a cool and dry environment
- Avoid prolonged exposure to high temperature and humidity
- Keep sealed after opening
- Minimize repeated temperature fluctuation
For international shipments, handling and transit conditions may affect enzyme stability depending on destination, customs clearance duration, and local climate conditions.

Applications
Lumbrokinase is widely used in:
- Dietary supplement formulations
- Enzyme ingredient systems
- Functional nutrition products
- Research and development applications
- Fibrinolytic enzyme-related formulations
Application suitability should be evaluated by the customer according to local regulations and intended use.
Packaging & Supply
Packaging
- Aluminum foil bag
- Fiber drum packaging available
- Customized packaging available upon request
Supply Information
- Sample: 100g available
- MOQ: 1.5 kg
- Delivery Time: Usually 7–15 days after payment
- Shipping: DHL / Air
- DDP shipping available for selected countries and regions
Quality & Documentation
Available supporting documents may include:
- COA
- Specification Sheet
- Product Information
- Batch Information
- Assay Method Information
Documentation availability may vary depending on market and application requirements.
Why Choose Allworms Bio-Tech?
- Specialized in earthworm-derived extracts
- Own earthworm cultivation base
- In-house extraction and production
- Stable raw material supply
- Focus on authentic lumbrokinase systems
- Support for international B2B customers
- Flexible supply and shipping solutions
FAQ
What is lumbrokinase used for?
Used in dietary supplements for circulation and cardiovascular support.
What method do you use to assay the activity?
Fibrin Plate Assay.
Is lumbrokinase stable during shipping?
Yes, with proper packaging and storage conditions.
Can you support bulk orders?
Yes, we provide stable large-scale supply.
Is your lumbrokinase blended with nattokinase?
Our product system is focused on pure earthworm-derived lumbrokinase.
Why do activity values differ between suppliers?
Different suppliers may use different assay methods, enzyme systems, substrates, and calculation standards. Activity values from different testing systems may not be directly interchangeable.
Are IU and FU directly convertible?
Not always. Different assay systems may produce significantly different numerical results depending on methodology and testing conditions.
Do you offer sample testing?
Yes. Samples are available for evaluation and compatibility testing.
Contact Us
If you are looking for a dedicated lumbrokinase manufacturer with controlled raw material sourcing and specialized earthworm extraction experience, please contact us for specifications, samples, and quotation details—-Send your massage to us: